ea0077oc1.6 | Reproductive and Neuroendocrinology | SFEBES2021
Johnson Gillian
, Onabanjo Caitlan
, Bousfield George
, Hardy Kate
, Jonas Kim
Ovarian ageing is a naturally occurring physiological process, marked by dynamic changes in ovarian function and hormone secretion. A key endocrine regulator of ovarian function is the heterodimeric glycoprotein hormone, follicle stimulating hormone (FSH). FSH is secreted as two glycosylation variants: partially glycosylated FSH (FSH21) and fully glycosylated FSH (FSH24). These variants have different in-vitro activities, with FSH21 more bioactive than FSH24. Interest...